Endocrine Abstracts

Diabetes mellitus type 1 (DM1), an autoimmune disease, affects an increasing number of young men in reproductive age. It has been estimated that its prevalence increases at a rate of ~3% per annum. Diabetes may affect male reproductive function by acting on the hypothalamic-pituitary-testicular axis, causing sexual dysfunction and disrupting male accessory gland function. According a recent study shows that men with DM1 have a smaller number of live births than controls. Despi...

Introduction: D-aspartic acid (D-AA) is involved in the regulation of spermatogenesis by influencing hormonal biosynthesis and secretion, resulting in an increased sperm concentration and progressive motility. Coenzyme Q10 (CoQ10) correlates positively with sperm concentration and motility at high concentrations, and it plays an antioxidant role, improving sperm motility and fertilization rate in ICSI cycles. Finally, low concentrations of zinc (Zn) have been found in azoosper...

Metabolic Syndrome (MetS) has been frequently associated with an overall inflammation status, called “metaflammation”, including atherosclerosis and non-alcholic steatohepatitis (NASH), In this study we aimed to evaluate the relationship between intra-prostatic inflammation and NASH in a cohort of patients affected by BPH. Between January 2012 and January 2016, 132 consecutive patients with BPH-related lower urinary tract symptoms (LUTS) who underwent transurethral r...

Importance: Early-onset androgenetic alopecia (AGA) has been suggested as a phenotypic sign of the male polycystic ovary syndrome (PCOS)-equivalent since men with this feature have a PCOS-like hormonal pattern. No study has evaluated the gonadal function of these men.Objective: To study the gonadal function of men with early-onset AGA and to identify suggestive criteria of male PCOS-equivalent.Design: This case-control study was co...